Welcome to CLEPAN

The aim of CLEPAN is to introduce medical students, clinicians without formal research training, and predoctoral students to basic clinical epidemiological concepts and analytic methods, without needing to learn an advanced computer program.

Become a CLEPAN user

Receive full access to
the CLEPAN platform and materials

Learn about

clinical medicine, epidemiology, and biostatistics
  • Measures of disease occurrence, outcome, and prognosis
  • Study designs
  • Sample size calculation
  • Data visualization
  • Bias and bias analysis
  • Interaction and effect-measure modification
CLEPAN system

Scientific Evidence

Sound scientific evidence is a prerequisite for any modern health service system to provide safe, high-quality patient care and to take maximum advantage of advances in diagnostics, treatment, rehabilitation, and prevention.

This evidence is derived best
from continually updated answers
to four key generic clinical questions

DIAGNOSIS

Which tests/examinations should be used to diagnose a disease and predict its course?

PROGNOSIS

What is the expected course of a disease without clinical intervention (natural history) or with treatment (clinical course)?

INTERVENTION

To what extent will a specific clinical intervention be beneficial in terms of curing or preventing a disease, slowing its progression, or reducing its symptom burden?

RISK-HARM

What are the risks - side effects, unintended adverse effects, complications - of selected treatments and interventions?

Addressing these questions

Addressing these questions requires integrated knowledge of clinical medicine, epidemiology, and biostatistics